Recently, Sirtex Medical Limited presented the SIRFLOX/FOXFIRE Global right-side survival data in metastatic colorectal cancer (MCRC)

Recently, Sirtex Medical Limited (ASX:SRX) presented the SIRFLOX/FOXFIRE Global right-side survival data in metastatic colorectal cancer (mCRC) at the 19th European Society for Medical Oncology (ESMO) World Congress on Gastrointestinal Cancer (WCGIC) in Barcelona, Spain. The combined SIRFLOX and FOXFIRE Global studies (n=530 and n=209, respectively) showed that for patients with a right-sided primary tumor, median Overall Survival (OS) was significantly improved with the addition of SIRSpheres Y-90 resin microspheres to standard chemotherapy versus chemotherapy alone [22.0 vs. 17.1 months, respectively; p=0.007; Hazard Ratio (HR): 0.64 (95% CI: 0.46-0.89)], but not for patients with a left-sided primary tumor [24.6 vs. 26.6 months; p=0.279; HR: 1.12 (95% CI: 0.92-1.36)]. There was no statistically significant difference in the baseline characteristics of patients who received SIR-Spheres microspheres plus chemotherapy versus chemotherapy alone.


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